- Cagney, James
- Calhoun, John C.
- Calloway, Cab
- Campbell, John A.
- Capone, Al
- Cardozo, Benjamin
- Carnegie, Andrew
- Carney, Art
- Carroll, Daniel
- Carter, Lillian
- Carter, Billy
- Carvel, Thomas
- Carver, George Washington
- Catt, Carrie Chapman
- Cazale, John
- Chadwick, Henry
- Chase, Samuel
- Chisholm, Shirley
- Chrysler, Walter
- Cianci, Vincent "Buddy"
- Clark, Abraham
- Clay, Henry
- Cleveland, Frances Folsom
- Cleveland, Grover
- Cleveland, Ruth
- Clifford, Nathan
- Clinton, DeWitt
- Clinton, George
- Clymer, George
- Coffelt, Leslie
- Cohan, George M.
- Cohn, Roy
- Colasanto, Nicholas
- Colfax, Schuyler
- Colgate, Bowles
- Colgate, William
- Collins, Harry Leon
- Collyer, Bud
- Colt, Samuel
- Conigliaro, Tony
- Connally, Nellie
- Connally, John
- Coolidge, Calvin
- Coolidge, Grace
- Cooper, John Sherman
- Cowen, Joshua Lionel
- Crawford, Joan
- Crockett, Davy
- Cronin, Joe
- Cummings, E. E.
- Currier, Nathaniel
- Curtis, Benjamin R.
- Curtis, Charles
- Curtis, John Bacon
- Cushing, William
