| Name | Tenure | Burial Location | Visited |
| Martha Washington | 1789-1797 | Mount Vernon, Virginia | 2003 |
| Abigail Adams | 1797-1801 | Quincy, Massachusetts | 2003 |
| Martha Jefferson Randolph | 1801-1809 | Charlottesville, Virginia | 2005 |
| Dolley Madison | 1809-1817 | Montpelier Station, Virginia | 2005 |
| Elizabeth Monroe | 1817-1825 | Richmond, Virginia | 2005 |
| Louisa Johnson Adams | 1825-1829 | Quincy, Massachusetts | 2003 |
| Emily Tennessee Donelson | 1829-1834 | Hermitage, Tennessee | 2013 |
| Sarah Yorke Jackson | 1834-1837 | Nashville, Tennessee | 2006 |
| Angelica Van Buren | 1838-1841 | New York, New York | 2019 |
| Anna Symmes Harrison | 1841 | North Bend, Ohio | 2004 |
| Letitia Christian Tyler | 1841-1842 | Roxbury, Virginia | |
| Priscilla Cooper Tyler | 1842-1844 | Montgomery, Alabama | 2013 |
| Julia Gardiner Tyler | 1844-1845 | Richmond, Virginia | 2005 |
| Sarah Childress Polk | 1845-1849 | Nashville, Tennessee | 2006 |
| Margaret Smith Taylor | 1849-1850 | Louisville, Kentucky | 2004 |
| Abigail Powers Fillmore | 1850-1853 | Buffalo, New York | 2005 |
| Jane Appleton Pierce | 1853-1857 | Concord, New Hampshire | 2005 |
| Harriet Lane Johnson | 1857-1861 | Baltimore, Maryland | 2015 |
| Mary Todd Lincoln | 1861-1865 | Springfield, Illinois | 2004 |
| Eliza Johnson | 1865-1869 | Greeneville, Tennessee | 2006 |
| Julia Dent Grant | 1869-1877 | New York, New York | 2004 |
| Lucy Webb Hayes | 1877-1881 | Fremont, Ohio | 2005 |
| Lucretia Garfield | 1881 | Cleveland, Ohio | 2005 |
| Mary Arthur McElroy | 1881-1885 | Menands, New York | 2014 |
| Rose Cleveland | 1885-1886 | Lucca, Italy | |
| Frances Cleveland | 1886-1889 | Princeton, New Jersey | 2004 |
| Caroline Scott Harrison | 1889-1892 | Indianapolis, Indiana | 2004 |
| Mary Harrison McKee | 1892-1893 | Indianapolis, Indiana | |
| Frances Cleveland* [1] | 1893-1897 | Princeton, New Jersey | 2004 |
| Ida Saxton McKinley | 1897-1901 | Canton, Ohio | 2005 |
| Edith Roosevelt | 1901-1909 | Oyster Bay, New York | 2004 |
| Helen Herron Taft | 1909-1913 | Arlington, Virginia | 2004 |
| Ellen Axson Wilson | 1913-1914 | Rome, Georgia | |
| Edith Bolling Galt Wilson | 1915-1921 | Washington, D.C. | 2004 |
| Florence Kling Harding | 1921-1923 | Marion, Ohio | 2005 |
| Grace Goodhue Coolidge | 1923-1929 | Plymouth Notch, Vermont | 2007 |
| Lou Henry Hoover | 1929-1933 | West Branch, Iowa | 2004 |
| Eleanor Roosevelt | 1933-1945 | Hyde Park, New York | 2004 |
| Bess Wallace Truman | 1945-1953 | Independence, Missouri | 2009 |
| Mamie Eisenhower | 1953-1961 | Abilene, Kansas | 2009 |
| Jacqueline Kennedy | 1961-1963 | Arlington, Virginia | 2003 |
| Lady Bird Johnson | 1963-1969 |
Stonewall, Texas | 2012 |
| Pat Ryan Nixon | 1969-1974 | Yorba Linda, California | 2008 |
| Betty Bloomer Ford | 1974-1977 |
Grand Rapids, Michigan |
|
| Rosalynn Smith Carter | 1977-1981 | ||
| Nancy Davis Reagan | 1981-1989 | Simi Valley, California | |
| Barbara Pierce Bush | 1989-1993 | College Station, Texas | 2019 |
| Hillary Rodham Clinton | 1993-2001 | ||
| Laura Welch Bush | 2001-2009 | ||
| Michelle Obama | 2009-2017 | ||
| Melania Trump | 2017- |